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Symbol
Name
ID
Pgap3
post-GPI attachment to proteins 3
MGI:2444461
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
decreased B cell proliferation
decreased T cell proliferation
increased T cell proliferation
impaired macrophage phagocytosis
abnormal T-helper 2 cell differentiation
abnormal T cell morphology
increased spleen germinal center number
abnormal CD4-positive, alpha-beta T cell physiology
increased susceptibility to experimental autoimmune encephalomyelitis
increased anti-double stranded DNA antibody level
increased anti-single stranded DNA antibody level
Availability Mouse Genotype
Pgap3tm1.1Ymra/Pgap3tm1.1Ymra *
Pgap3tm1Ymra/Pgap3tm1Ymra
Cd19tm1(cre)Cgn/Cd19+  (conditional)
*
Pgap3tm1Ymra/Pgap3tm1Ymra
Tg(Lck-cre)#Jxm/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory